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Sr. Scientist, Antibody Engineering @ Scholarrock

Cambridge, Massachusetts, USOnsiteFull-time
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About this role

Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.

As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at ScholarRock.com and follow @ScholarRock on X and on LinkedIn.

Summary of Position: At Scholar Rock, we strive to develop best-in-class antibody-based therapeutics across multiple disease areas by leveraging our Antibody Engineering and Structural Biology expertise. Scholar Rock is seeking highly motivated, energetic and collaborative Senior Scientist to join the Antibody Discovery and Engineering group. The successful candidate will design and execute antibody discovery and optimization campaigns using phage display and yeast display technology, contribute to the development and application of display-based screening strategies, and advance high-quality leads through biochemical and biophysical characterization. Hands-on experience with phage display is required; experience with yeast display is preferred. Experience in recombinant protein purification and characterization are highly desirable.

Skills

ResearchAntibody Discovery and Engineering

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