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Careers at University of East Anglia
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511 positions at University of East Anglia
PhD Studentship: Chemical Biology to target bacteria: Inhibiting bacterial growth by controlling cell division protein interactions
University of East Anglia·Norwich
Primary Supervisor - Dr Andrew Beekman Antibiotic-resistant pathogens are a huge threat in healthcare and farming. The last resorts of conventional antibiotic drugs are unable to treat multi-resistant strains in patients. New approaches towards antibiotics are desperately needed.…
PhD Studentship: How to build an immune receptor: AI-led protein design for engineering disease resistance
University of East Anglia·Norwich
Primary Supervisor - Professor Mark Banfield Like animals, plants get sick, but they have an immune system to fight back against infection. Plant diseases are a threat to food production and a constraint on achieving food security against the background of a changing climate and …
PhD Studentship: Whole genome sequencing from mosquito blood meals
University of East Anglia·Norwich
Primary Supervisor - Dr Anders Bergstrom Mosquitos can be seen as tiny, autonomous samplers of blood from wild animals. It is well-established that mosquito blood meals contain animal DNA, as well as DNA from animal pathogens. Current environmental DNA (eDNA) techniques are routi…
PhD Studentship: Click-to-Connect Cytochromes: Modular Components for Sustainable Electrical Circuits
University of East Anglia·Norwich
Primary Supervisor - Professor Julea Butt This exciting project will engineer cytochromes for site-selective covalent linkage to multiple redox partners and electrodes thereby delivering proof-of-principle for novel electronic circuitry. Harnessing redox-active proteins as an abu…
PhD Studentship: How do fungi and bacteria communicate? Decoding the rules of cross-kingdom microbial interactions
University of East Anglia·Norwich
Primary Supervisor - Professor Alessia Buscaino Microorganisms rarely live alone. Instead, fungi and bacteria form complex communities where they constantly communicate, compete and cooperate. These cross kingdom interactions are increasingly recognised as key regulators of micro…
PhD Studentship: Decoding the molecular switches that control fungal growth and infection
University of East Anglia·Norwich
Primary Supervisor - Dr Stefan Bidula Fungal infections are responsible for over 1.5 million deaths each year, cause substantial agricultural losses, and are becoming increasingly difficult to treat due to rising antifungal resistance. To develop the next generation of antifungal…
PhD Studentship: Cracking the carbohydrate code: how carbohydrate-binding modules control starch digestion
University of East Anglia·Norwich
Why this matters: Starch is the principal source of dietary glucose, and the rate at which it is digested has major consequences for metabolic health. Food science still lacks the mechanistic understanding to rationally design starch-based foods with tailored digestion profiles. …
PhD Studentship: Breaking Code: Deciphering the Biology of the Selfless Virus-like Gene Transfer Agents
University of East Anglia·Norwich
Bacteria commonly exchange genetic information (DNA) in a process called horizontal gene transfer as they evolve and adapt to changes in their local environment. Understanding horizontal gene transfer and how new genetic information is incorporated and domesticated into the exist…
PhD Studentship: Engineering protein nanocages for biotechnology applications
University of East Anglia·Norwich
Proteins that self-assemble to yield cage-like structures are of great interest due to their potential applications in biotechnology. The cellular protein ferritin, which functions to detoxify and store iron, is composed of 24 subunits, arranged in a highly symmetric fashion to f…
PhD Studentship: Where does Salmonella hide? Using Organ-on-Chip technology to uncover the secrets of persistent infection
University of East Anglia·Norwich
Persistent asymptomatic infections remain an important but poorly understood public health challenge. Salmonella infections can become persistent, contributing to ongoing transmission, recurrent disease and potential prolonged antimicrobial exposure. Yet the mechanisms enabling n…
PhD Studentship: Decoding and Designing DNA Replication Origins Using Genome Language Models
University of East Anglia·Norwich
Project Supervisor - Dr Conrad Nieduszynski How does a cell know where and when to copy its DNA? And can we use artificial intelligence to design entirely new genetic elements that control this process? This exciting interdisciplinary PhD project will tackle a fundamental questio…
PhD Studentship: The Cardiac Positioning System – How Do Heart Progenitors Find Their Way?
University of East Anglia·Norwich
Primary Supervisor - Professor Andrea Munsterberg The first organ to develop in vertebrate embryos is the heart, when two streams of cardiac progenitor cells undertake an epic migration before reuniting at the heart field – the site of future heart formation. How do cardiac proge…
PhD Studentship: Listening to La Soufrière: Fibre Optics and AI for the Next Generation of Volcano Monitoring
University of East Anglia·Norwich
Scientific Background A major challenge in volcanology is understanding and anticipating transitions in volcanic activity. Subtle changes within volcanic systems can precede hazardous eruptions, yet remain difficult to detect and interpret. This challenge is the focus of the NERC…
PhD Studentship: Manipulating Meiotic Crossover Control in Wheat
University of East Anglia·Norwich
Primary Supervisor - Dr Chris Morgan Meiotic recombination generates the genetic diversity on which both evolution and crop breeding depend. In wheat and other cereals, crossovers are strongly biased towards certain regions of the genome, leaving vast stretches almost untouched. …
PhD Studentship: From climate information to climate action: Evaluating how climate information use shapes local adaptation decision making in English Local Authorities and opportunities for improv...
University of East Anglia·Norwich
The Climate Change Committee’s Well Adapted UK report highlights a critical need for practical adaptation solutions to build a resilient UK by 2050. Although information and data to inform adaptation planning is increasingly available through national risk assessments and climate…
PhD Studentship: Understanding the Evolution of How Plants Perceive Changes in the Environment
University of East Anglia·Norwich
Scientific Background Plants modify the concentration of calcium ions in their cells in response to different environmental stimuli and stresses. These changes in cellular calcium concentration trigger many downstream responses, including re-programming of gene expression and coo…
PhD Studentship: Across land, oceans and the atmosphere: Decoding Earth's carbon cycle with CO2 polyisotopologues
University of East Anglia·Norwich
Scientific background: Carbon dioxide (CO2) is the most important anthropogenic greenhouse gas. The 2015 Paris Agreement aims to avoid dangerous climate change by reducing emissions of CO2 and other greenhouse gases. Independent top-down constraints on emissions require accurate …
PhD Studentship: Dust, the Atlantic Ocean, and Climate
University of East Anglia·Norwich
Scientific background The Atlantic Ocean has warmed significantly over the last few years partly from increasing greenhouse gases, but other climate forcing agents also play a role. In particular, dust produced and lifted into the atmosphere over Africa and transported thousands …
PhD Studentship: Where do plants make their medicine? Mapping chemical defence one cell at a time
University of East Anglia·Norwich
Primary Supervisor - Dr Tatsuya Nobori When a pathogen attacks, a plant fights back with chemistry. However, not every cell uses the same defence. Our recent single-cell study revealed an unexpected division of labour in infected leaves: different groups of cells activate genes f…
PhD Studentship: How Do the Connections Between a Cell and its Neighbours Control How a Cell Responds?
University of East Anglia·Norwich
Plant cells are connected to their neighbours via ‘tubes’ called plasmodesmata, creating an interconnected cytoplasm that joins cells within and between tissues and organs. Many molecules use plasmodesmata to move freely between cells and it is critical for a plant to tightly con…
PhD Studentship: Running on Empty: Metabolic Ageing in Blood Stem Cells
University of East Anglia·Norwich
Every blood cell in your body, from oxygen-carrying red cells to virus-fighting white cells, begins life in a rare population of blood stem cells that must stay active for an entire lifetime. As we age, these stem cells lose their edge, contributing to the immune decline and bloo…
PhD Studentship: Functional Genomics of Sexually Antagonistic Selection
University of East Anglia·Norwich
Why do harmful genes persist in populations instead of being removed by natural selection? One answer lies in sexual antagonism: when a genetic variant benefits males but harms females, or vice versa. This genetic tug-of-war is one of evolution’s most intriguing puzzles. It can c…
PhD Studentship: How does NRP2 keep blood vessels sealed and calm under stress?
University of East Anglia·Norwich
Blood vessels are lined by endothelial cells, which form a living barrier between blood and tissues. These cells must stay tightly connected, sense blood flow, respond to nutrients and communicate with immune cells, while avoiding unnecessary inflammation. How endothelial cells m…
PhD Studentship: Engineering Fitness in Disease-Resistant Crops
University of East Anglia·Norwich
Engineering crop disease resistance to overcome the growth-defence trade-off Developing crops that are both productive and resillient is one of the major challenges facing agriculture. While disease-resistance genes can protect plants from devastating pathogens, they often come w…
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