About this role
ExcepGen is seeking a talented and motivated Research Associate to join its San Francisco team, working collaboratively with senior scientists to advance the company’s drug discovery research programs.
This is a unique opportunity to join an early-stage biotechnology startup and take on a wide range of responsibilities. The successful candidate should have the ability and willingness to work across a variety of functional areas. This position reports to the Chief Scientific Officer.
Key Responsibilities:
Maintain mammalian, insect, and plant cell culturesTransfect cell lines for generation of stable cell lines or expression of recombinant proteinsPurify recombinant proteins using standard purification technologiesPerform in vitro functional assays as well as biophysical and/or cell-based binding assaysExecute a range of experiments using molecular biology techniques such as plasmid design, nucleic acid and protein isolation, PCR and cloningDocument all experimental procedures and results in an electronic laboratory notebookUse basic technical discretion to troubleshoot experiments with senior scientistsReview data, prepare reports, and communicate experimental results to manager and in team meetingsMaintain lab operations such as ordering, organizing, and restocking reagents, equipment, and other supplies Education & Experience:
B.S. or M.S. in Biology, Cell Biology, Biochemistry, or equivalent scientific discipline1-3+ years of full-time laboratory experience in an industrial or academic settingSkills & Competencies:
Experienced in mammalian culture techniques including transfection and cell based functional assaysExperienced in standard protein purification technologies including Affinity- and Size-Exclusion chromatography using an AEKTA-FPLC system, SDS-PAGE and Western blotAbility to interpret and clearly understand SOPs and laboratory proceduresStrong analytical and problem-solving skillsDetail-oriented with meticulous record-keepingAbility to coordinate and prioritize tasks across multiple projects to meet deadlinesWorking knowledge of data analysis software like Excel, Graphpad, or othersAbility to adapt in a fast-paced startup environment and execute projects independentlyWillingness to work occasional weekends when needed for experimentsAlignment with ExcepGen’s culture and valuesCompliance with all laboratory health and safety proceduresNice to Have:
Experience with general molecular biology techniques and approaches, including molecular cloning methods, PCR/qPCR, and primer design. Experience writing protocols and maintaining detailed laboratory notebooksExperience in expressing and purifying membrane proteins and protein complexesKnowledge in maintaining and culturing insect-, plant- and yeast cellsAbility to research new scientific areas and design protocolsOther information about ExcepGen:
ExcepGen launched out of Y Combinator in March 2019 with innovative technology for drug development. The company is based in downtown San Francisco.
Our values:
Make something exceptionalBe in it togetherThink critically, work creativelyEmbrace continuous improvementFocus on output, not hoursDo the right thing, alwaysCompany Benefits:
Opportunity to work in a small, collaborative team at an early-stage companyCompetitive salary and stock optionsHealthcare, dental, vision, and life insurance benefitsPaid vacation, sick time, and holidays All your information will be kept confidential according to EEO guidelines.