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CAR-T Clinical Fellow – Haematology @ University College London Hospitals NHS Foundation Trust

London, England, GBOnsiteContractJob reference C9309-26-0900
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About this role

Job summary

These roles are set within the department of malignant haematology at UCLH with a focus on cellular therapy (including CAR-T) in accordance with JACIE accreditation standards and NHSE guidance. The T-cell Immunotherapy service at UCLH is undergoing significant expansion and the post-holder will be involved in the delivery of (1) licenced/NHSE CAR T-cell products; (2) the academic and commercial CAR T-cell trial portfolio and (3) a portfolio of TCR-transduced T-cell and Tumour Infiltrating Lymphocyte (TIL) therapies for solid tumours which we hope to further cultivate and develop through the appointments.

There will be training in trial design and delivery through involvement in Tumour Management Group meetings for the academic trial portfolio alongside attendance at Site Initiation Visits for new studies. Training regarding the function of apheresis and the stem cell lab will also be provided.The appointments will be initially for a period of 1 year from February / March 2027 with the potential for renewal on an annual basis. The roles will provide structured training in cellular therapy and it will be possible for applicants to develop a research project with a view to undertaking an MD/PhD. There will be an honorary contract with the UCL Cancer Institute for the post-holders.

Main duties of the job

These roles are set within the department of malignant haematology at UCLH with a focus on cellular therapy (including CAR-T) in accordance with JACIE accreditation standards and NHSE guidance. UCLH is an international leader in the delivery of cellular immunotherapies and the post-holder will be involved in the delivery of (1) licenced CAR T-cell products; (2) the academic and commercial CAR T-cell trial portfolio including trials in haematological malignancies and autoimmune diseases and (3) a portfolio of CAR T-cell, TCR-transduced T-cell and Tumour Infiltrating Lymphocyte (TIL) therapies for solid tumours which we hope to further cultivate and develop through the appointments.

UCLH has an extensive cellular therapy clinical trial portfolio and the post holder will receive training and gain comprehensive experience of trial conduct from trial set up through to long term follow-up. Training regarding the function of apheresis and the stem cell lab will also be provided.

About us

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.

We provide first-class acute and specialist services across eight sites:o University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)o National Hospital for Neurology and Neurosurgeryo Royal National ENT and Eastman Dental Hospitalso University College Hospital Grafton Way Buildingo Royal London Hospital for Integrated Medicineo University College Hospital Macmillan Cancer Centreo The Hospital for Tropical Diseaseso University College Hospital at Westmoreland Street

We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women's health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.

We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.

Job description Job responsibilities

For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.

Please note, due to anticipated high volumes of applications, this vacancy may close earlier than the listed closing date. You are advised not to delay submitting your completed application Come and be a part of the best NHS trust in England to work for, according to our staff*

* UCLH top trust to work at in England - In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England for the third year in a row.

UCLH recognises the benefits of flexible working for staff To find out more, visit: Flexible working.

To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?

Person Specification

Knowledge and Qualifications Essential

Medical degree Membership of the Royal College of Physicians or equivalent Eligible for GMC registration NB: Non-UK trained doctors must be on the GMC register by date of appointment having completed both PLAB1 & 2 and hold a current licence to practise. Completed core medial training or equivalent to ST6 at appointment

Desirable

Knowledge of the Clinical Governance framework of the NHS (including Research governance) and understanding of current changes in the organisation and management structures of the NHS. Ability to act within these parameters

Experience Essential

Experience of teaching at undergraduate and postgraduate levels Clinical audit experience

Desirable

Undergoing or completed higher specialist training in Haematology Experience in oncology Experience of clinical trials

Skills and Abilities Essential

Ability and commitment to teach in a clinical setting Ability to organise and prioritise workload, to delegate responsibility as appropriate and to supervise staff Good inter-personal skills with an ability to work co-operatively in a multidisciplinary setting Ability to work effectively within a team environment & on own initiative Understanding of research methodology

Communication Essential

Excellent communication skills/verbal and written. Good command of written and spoken English

Disclosure and Barring Service Check This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details Employer name University College London Hospitals NHS Foundation Trust

Address University College Hospital Grafton Way Building

1 Grafton Way

London

WC1E 6AS

United Kingdom

Employer's website https://www.uclh.nhs.uk (Opens in a new tab)

Skills

NHSHealthcareFixed-TermFoundation Trust

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