About this role
Pivotpark Senior Scientist Neuroscience Synaffix (Lonza) Prime objective of the ADS-R&D Bioconjugates Research function (Oss) is to provide best-in-class targeted delivery technologies, i.e. development of protein conjugation technologies, linkers and payloads. General focus is on ADCs, however other modalities to be employed in indications such as immuno-oncology, targeted gene therapy, neuromuscular disease, neurodegeneration are also being pursued. A Senior Scientist Neuroscience will play a key role in giving direction to and implementing of the R&D agenda of Bioconjugates Research in the field of neuroscience and neurodegeneration. The Senior Scientist Neuroscience is an experienced professional who has impact on their own team as well as closely related work teams in organic chemistry and biochemistry. The Senior Scientist Neuroscience is accountable for the performance and results in the assigned projects including timelines, costs control and the development of the team. What you will get: - An agile career and dynamic working culture. - An inclusive and ethical workplace. - Compensation programs that recognize high performance. - A variety of benefits dependent on role and location. The full list of our global benefits can be found here. The full-time annual base pay for this position in The Netherlands is expected to range between 60.750,- EUR and 85.050,- EUR . Initial salary placement within this range will be determined based on role‑related factors such as experience, qualifications, and expected contribution. What you will do: - In the context of enhancement of blood-brain-barrier (BBB) crossing, evaluates transcytosis mechanisms, i.e. receptor-mediated transport (RTM, e.g., TfR1, CD98hc, IGF1R) - Proposes strategies in complex bioconjugations. Applies concepts published in literature beyond the original scope. Performs molecular engineering support. Performs complex enzymatic and chemical reactions on antibo...