About this role
A 3-year researcher position funded by the South-Eastern Norway Regional Health Authority is available at the Department of Immunology, Oslo University Hospital. The successful candidate will join a multidisciplinary team developing antibody-based immunotherapies against invasive fungal diseases (IFDs) — infections by pathogens such as Candida, Aspergillus and Cryptococcus spp. that remain a major cause of mortality in immunocompromised patients.Antifungal defense depends on the coordinated action of T cells, B cells and antibodies, yet how these arms cooperate — and why antibodies to the same fungal antigen can be protective, inert, or disease-enhancing — remains poorly defined. The lab combines antibody engineering with in vivo models and advanced imaging to address this.The position centres on engineering antibodies to strengthen immune defense against fungi, using this as a tool to understand how antibody responses can help restore protection in immunodeficiency states such as neutropenia or phagocyte dysfunction. The successful candidate will also help develop antibody-based probes and imaging tools to detect, visualize and quantify fungal infection and immune-cell engagement in vitro and in vivo, and will use the lab’s B cell receptor (BCR) knock-in platform, alongside matching T cell models, to study how B and T cell responses shape antifungal immunity.Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and we encourage all qualified candidates, regardless of background, to apply!