About this role
The Role: BigHat is seeking an exceptional and highly experienced individual for a position as Director/Senior Director of Antibody Discovery. This individual will lead the company’s antibody discovery and display function. They will be responsible for conceiving of and leading multi-year team and technology strategy as well as managing routine operational execution for identification and maturation of high-quality antibodies across antigen types for both BigHat and BigHat-partnered therapeutic research programs. Lead BigHat’s antibody discovery and display functions, setting the scientific, technical, and strategic direction Oversee the routine execution of display-based selection campaigns to enhance and diversify affinity, developability, and function across diverse antibody formats and antigen types in support of BigHat and BigHat-partnered therapeutic programs Manage and mentor a team of scientists responsible for antibody library design, generation, screening, selection, and early optimization Shape and expand BigHat’s antibody discovery technologies and capabilities, including new display and selection methods, library design strategies, and technical approaches that leverage and enhance the company’s integrated experimental and computational platform Provide scientific leadership across discovery and early optimization efforts, ensuring antibodies emerging from selections possess strong functional and developability characteristics Work closely with leaders in Protein Sciences, Data Science/Machine Learning, Engineering, and Platform groups to ensure seamless progression from discovery through characterization and optimization Collaborate with biology and therapeutic research leads to ensure display outputs align with and advance program objectives Foster a collaborative and high-performance culture within the discovery organization