About this role
Synthetic DNA Process Development Scientist Include but are not Limited to the Following:
We are seeking a highly skilled and motivated Organic Chemist with expertise in oligonucleotide synthesis and purification to support process development and manufacturing. This role focuses on developing, optimizing, and scaling chemical processes for high-throughput and high-quality oligonucleotide production.
Design, develop, and optimize chemical synthesis processes for nucleotides and oligonucleotidesProcess development and scale-up from R&D to manufacturingDevelop and improve oligonucleotide purification processes (e.g., HPLC, ion-exchange, desalting)Troubleshoot synthesis and purification challenges to improve yield and purityCollaborate with manufacturing, QC, and engineering for process transferEvaluate new chemistries and technologiesAuthor SOPs, batch records, and technical reportsEnsure compliance with quality systemsMentor lab technicians Basic Minimum Education Qualifications:
Ph.D. or Master’s degree in Organic Chemistry or related field (required)Basic Minimum Work Requirements:
Minimum 5 years of industrial experience in chemical synthesisHands-on experience with solid-phase oligonucleotide synthesisHands-on experience in oligonucleotide purification process developmentStrong analytical skills (HPLC, LC-MS)Experience scaling processes to manufacturingExperience in GMP or regulated environments, preferredFamiliarity with automated DNA/RNA synthesizers, strongly preferredKnowledge of modified nucleotides, strongly preferredExperience in high-throughput oligo production, strongly preferredAuthorization to work in the United States indefinitely without restriction or sponsorship.The Ideal Candidates Possess the Following:
Fast-paced, collaborative environmentAbility to manage multiple prioritiesOccasional off-hours support as needed Position is full-time working Monday - Friday 8:00am - 5:00pm, with overtime and weekend work as needed. Candidates currently living within a commutable distance of Louisville, KY are encouraged to apply.
Excellent full-time benefits including comprehensive medical coverage, dental, and vision optionsLife and disability insurance401(k) with company matchPaid vacation and holidays#LI-KS1
Eurofins USA Genomic Services is a Disabled and Veteran Equal Employment Opportunity employer.