About this role
Dissecting the Interplay Between Senescence and Antitumor Immunity in Liver Cancer
About us
The CRUK Scotland Institute is a cancer research institute, situated in Glasgow with approximately 250 researchers split across 30 research groups consisting of PIs, postdoctoral scientists, PhD students and scientific officers. It is one of Europe's leading cancer research centres, supporting cutting-edge work into the molecular mechanisms of cancer development. As well as core support from Cancer Research UK, the Institute also receives an additional third of its total income from external grants and industry collaborations. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis.
Project Outline
Join the newly established laboratory of Dr Riccardo Mezzadra, launching in March 2027 and funded through a CRUK Career Development Fellowship. Dr Mezzadra's research focuses on understanding how conventional cancer therapies reshape anti-tumour immune responses, with particular expertise in T cell immunology, tumour-immune interactions, and in vivo models of cancer.
This is a unique opportunity to become an early member of a new research group investigating how conventional cancer therapies influence anti-tumour immunity and responses to immunotherapy. Working closely with the Group Leader and other members of the laboratory, you will play a central role in generating and analysing data from in vivo studies, cell culture and molecular biology experiments, while helping to establish the laboratory's protocols, systems and ways of working from the outset.
Key Responsibilities
- Conduct and support in vivo and in vitro experiments using mouse models of cancer and mouse and human cell lines.
- Generate, collect and analyse experimental data using a range of cellular and molecular biology techniques.
- Play a key role in establishing new laboratory protocols, experimental workflows, reagents and model systems.
- Support the day-to-day operation of the laboratory, including management of stocks, inventories and shared resources.
- Collaborate effectively with colleagues across the Institute and contribute to a positive and productive research environment.
- Contribute to the delivery of the laboratory's research objectives and the dissemination of research findings.
About You
Essential
- Bachelor's or Master's degree in biomedical sciences, cell biology, immunology, or a related discipline.
- Experience of laboratory-based experimental research.
- Good working knowledge of molecular biology techniques.
- Strong organisational, communication and teamwork skills.
- Ability to work independently while contributing effectively within a multidisciplinary research team.
Desirable
- Experience of tissue culture, flow cytometry, cancer biology, animal research, or molecular biology techniques.
- Experience working with mouse models of cancer.
- Previous laboratory management or laboratory organisation experience.
For informal enquiries, please email Dr Riccardo Mezzadra at [email protected]
Applications must be made via our website by clicking on the 'Apply' button above.
Closing date: 4th December 2026