About this role
Job Description
ATTENTION MILITARY AFFILIATED JOB SEEKERS - Our organization works with partner companies to source qualified talent for their open roles. The following position is available to Veterans, Transitioning Military, National Guard and Reserve Members, Military Spouses, Wounded Warriors, and their Caregivers. If you have the required skill set, education requirements, and experience, please click the submit button and follow the next steps. Unless specifically stated otherwise, this role is "On-Site" at the location detailed in the job post.
Associate Manufacturing (Pilot Plant)
Let’s do this. Let’s change the world. In this vital role you will support the execution of cell culture, harvest, and purification process studies at the 500L scale, to include operation of single-use bioreactors, centrifugation equipment, chromatography skids and filtration systems. The Amgen Rhode Island AR6 Pilot Plant provides critical technical support for team supply, commercial process development, technology transfer, process characterization, and scale-up/scale-down activities.
This is a day shift position that includes off shift and weekend coverage.
Role Responsibilities
Aseptically maintain mammalian cell culture through vial thaw, flask passaging, bioreactor operations to harvest, which may include, but not limited to; centrifugation, multistage clarification and/or ATF (Alternating Tangential Flow) filtration
Protein purification via multi-stage chromatography and filtration systems to include, but not limited to; Ion-Exchange Chromatography (IEX), Affinity Chromatography and Tangential Flow Filtration
Set-up and operation of bioreactors and vessels, centrifugation and filtration harvest equipment and downstream equipment to include, but not limited to; chromatography and Ultra Filtration Diafiltration (UF/DF) skids
Perform bench-work studies such as titration and filtration
Perform in-process sampling and monitoring
Analyze in-process samples and perform routine analytical equipment maintenance
Perform batch and filtration of media and buffers
Perform new product introductions (NPI), technology transfer and participate in equipment or experiment design
Perform documentation of experimental data in electronic lab notebooks in accordance with Good Laboratory Practices (GLP)
Perform general lab organization and cleaning
Management of inventory, operational excellence (OE) initiatives and preventative maintenance for systems and equipment
Inform-role for operational decision making, troubleshooting and investigative work.
Additional Qualifications/Responsibilities
Basic Qualifications
Bachelor’s degree OR
Associate’s degree + 6 months of biotechnology in manufacturing, engineering, or process development work experience OR
High school diploma / GED + 2 years of biotechnology in manufacturing, engineering, or process development work experience
Preferred Qualifications
An established record of encouraging safety in a lab or manufacturing setting
Experienced in performing bioprocess unit operations in cell culture and/or purification
Knowledge in troubleshooting process equipment issues including automation control strategies and utilities such as clean in place (CIP) and clean steam
Experience in the operation of control systems (Delta V) and method development on Cytiva purification systems using Unicorn
Experience with data analysis and interpretation
Experience collaborating with and across functional areas and sites
Strong written and verbal communication skills; strong computer skills
Experience in leading Operational Excellence (OE) efforts to drive efficiency and safety
Salary Range
70.985,20USD -96.038,80 USD