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Bioinformatics (f/m/d) (Bioinformatiker/in) @ CeCaVa GmbH

Tübingen, DE142, DEOnsiteFull-time
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About this role

cecava, a biopharmaceutical immuno-oncology company based in Tübingen (Germany) currently preparing to conduct first clinical trials, is searching for a motivatedBioinformatics (f/m/d)in full timececava is developing personalized cancer immunotherapies derived from tumor-specific mutations that give rise to neoepitopes.

The successful candidate will be responsible for analyzing biomedical data and for developing, validating, and refining computational pipelines for Next-Generation Sequencing (NGS) analyses and neoepitope prediction and selection, to support cecava’s clinical trials.

  • Your field of responsibility- Together with the bioinformatics team, develop, validate, and refine computational pipelines for NGS analyses and neoepitope prediction & selection - Support the documentation, testing and validation of computational pipelines in line with internal quality and regulatory standards- Run bioinformatics pipelines in a GxP-regulated environment to support clinical trials- Organize biomedical data (including database construction) and conduct statistical analyses and visualizations- Strengthen the bioinformatics unit of the company and work within an interdisciplinary teamOur expectations- Degree in Bioinformatics (MSc or PhD; alternatively, a BSc degree with at least 2 years of relevant work experience) - Hands-on experience in programming, constructing, and containerizing pipelines and workflows- Practical experience in programming and running workflows for NGS data analysis (ideally WES, WTS and somatic mutation calling; scRNA-Seq, TCR-Seq, etc. is a plus)- Experience in software testing, validation and benchmarking is a plus- Sound skills in scientific data processing, statistics, data analysis, and visualization- Proficiency in Python and R (SQL is a plus)- Ideally, hands-on experience in conceptualizing, programming, training and testing ML models- Knowledge of GxP-regulations and/or GAMP5 framework is a plus- Biological background, ideally in oncology, immunology, or immuno-oncology - Self-motivated team player with independent working style and excellent problem-solving skills- Good working knowledge of German and English (verbally and in writing)Our offer- An exciting opportunity to contribute to the development of a disruptive technology for the benefit of cancer patients- Work within a dedicated team in an entrepreneurial, innovative, and open-minded working atmosphere- Flat hierarchies and easy access to all company functions- Free drinks and fresh fruits- Job bike and Job ticket (Deutschlandticket)Your applicationPlease send your complete application (including cover letter, CV, certificates, expected availability date, salary expectations, a complete list of publications and 2-3 references) by email and in one PDF document to [email protected] .We look forward to receiving your application

Skills

NGS data analysisneoepitope predictionPythonRSQLSoftware TestingvalidationBioinformatics pipelinesscRNA-seqTCR-seqWESWTS

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