About this role
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Overview
The Clinical Research Nurse 2 will be the primary interface between the Principal Investigator and all aspects of study implementation. Key responsibilities include planning, tracking, and ensuring that the clinical activities for study participants are conducted in accordance with approved protocols. These activities include, but are not limited to patient screening, eligibility determination, registration and other protocol and subject milestones including supervising and ensuring high fidelity collection and storage of data and biospecimens. The CRN II will have direct patient contact and is responsible for managing and performing the clinical and operational aspects of moderately to complex protocols.
Schedule/Shift: Full-time, 37.5 hours, operating clinical hours are M-F 8:30 am – 5:30pm. Early mornings, evenings, weekends, holidays/recess may also be required.
Required Skills and Abilities
1. Ability to build, review and approve accurate and complete order sets to ensure compliance with individual research protocols and ensure timely activation of research trials. 2. Proven ability to develop and participate in the delivery of training for new protocols, including; the creation of training materials, protocol-specific work sheets, nursing in-service presentations and others as required by specific protocols. Tracks and reports adverse events, serious adverse events, protocol waivers, deviations, and violations. 3. Ability to assess protocols for feasibility and determine complexity, identify risks, logistics and challenges associated with operationalizing and implementing specific trials at Yale New Haven Hospital and other Yale New Haven Health locations. 4. Proven ability to manage several projects concurrently while balancing competing priorities and deadlines. Direct the prioritization as it relates to the building and approval of drug order sets and lab order templates. Direct the prioritization and approve OnCore study calendars. 5. Strong understanding of Cardiac conditions including disease-related symptom management, standard treatment options and treatment-related side effect management.
Preferred Skills and Abilities
1. MSN and experience with cardiology research.
Principal Responsibilities 1. Evaluates and assesses subject’s suitability for inclusion in studies; develops and modifies procedures according to study findings; recommends changes to the study protocol to coincide with study goals and objectives. 2. Develops and implements procedures and data quality assurance standards for safety monitoring components of studies. 3. Contributes to designing activities, policies and procedures to improve day to day efficiency of the recruitment and assessment components of the study and to ensure that staff members perform activities within established research protocol. 4. Arranges patient enrollment, determines patient eligibility and obtains informed consent. 5. Develops study subject referral sources; designs and develops outreach programs. 6. Collaborates with multidisciplinary researchers to coordinate research programs that integrate new advances in clinical trials. 7. Delegates tasks and supervises the activities of other licensed and unlicensed care providers. 8. May perform other duties as assigned.
Required Education and Experience
Bachelor’s of Science Degree in Nursing and four years of related experience or an equivalent combination of education and experience.
Required License(s) or Certification(s)
Licensure as Registered Nurse in the State of Connecticut or Connecticut license eligible. Job Posting Date 10/15/2026 Job Category Professional Bargaining Unit NON Compensation Grade Clinical & Research Compensation Grade Profile Clinical Research Nurse 2 (24) Salary Range $68,000.00 - $120,500.00 Benefits A general description of the benefits to be offered with this Managerial & Professional position is available at: Yale Benefits
Time Type Full time Duration Type Staff Work Model On-site Background Check Requirements
All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website.
Health Requirements
This role is a healthcare worker position. Healthcare workers (HCW) are defined as university employees working a healthcare setting who have the potential for direct or indirect exposure to patients, human research subjects or infectious materials including body substance, contaminated medical supplies, devices and equipment, surfaces, or air. HCW have specific health requirements that must be met prior to starting work, including MMR vaccine or immunity, varicella (chickenpox) vaccine or immunity, TB screening, COVID vaccine according to University policy, hepatitis B vaccine or immunity, and annual flu vaccination.
Posting Disclaimer
Salary offers are determined by a candidate’s qualifications, experience, skills, and education in relation to the position requirements, along with the role’s grade profile and current internal and external market conditions.
The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the position. Employees will be assigned specific job-related duties through their hiring department.
The University is committed to basing judgments concerning the admission, education, and employment of individuals upon their qualifications and abilities and seeks to attract to its faculty, staff, and student body qualified persons from a broad range of backgrounds and perspectives. In accordance with this policy and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment against any individual on account of that individual’s sex, sexual orientation, gender identity or expression, race, color, national or ethnic origin, religion, age, disability, status as a special disabled veteran, veteran of the Vietnam era or other covered veteran.
Inquiries concerning Yale's Policy Against Discrimination and Harassment may be referred to the Office of Institutional Equity and Accessibility (OIEA).
Note
Yale University is a tobacco-free campus.