About this role
For a leading pharmaceutical company, we are looking for a qualified
Lead Chemical Process R&D Scientist (m/f/d)
General Information: • Location: Basel • Workload: 100% • Start: ASAP • Duration: 12 months (extension possible) • Home Office: up to 40% • Travel: Occasional travel (up to 4 trips per year) to CDMOs in Europe or Asia
Your Responsibilities: • Lead chemical process research and development activities for clinical-stage pharmaceutical projects, with a strong focus on late-stage development and process optimization. • Manage and guide internal process chemistry teams of up to five scientists and associates in a matrix leadership role. • Oversee external development and manufacturing activities at CDMOs, ensuring alignment with project objectives, timelines, quality standards, and budget expectations. • Drive synthetic route scouting, process optimization, process understanding, scale-up activities, and delivery of drug substance material. • Coordinate internal and external stakeholders to ensure timely, safe, and cost-effective supply of APIs and advanced intermediates. • Lead technology transfer activities from development to manufacturing environments. • Ensure all activities comply with safety, quality, regulatory, and sustainability requirements. • Utilize scientific expertise and data-driven approaches to support process development decisions and project strategy. • Contribute to project planning, risk assessment, technical documentation, and cross-functional decision-making.
Your Profile: • PhD or Postdoctoral qualification in Synthetic Organic Chemistry. • Minimum 5 years of pharmaceutical chemical process R&D experience, with demonstrated expertise in late-stage process development and scale-up. • Proven track record of leading scientific teams and driving project deliverables within process chemistry organizations. • Strong experience managing external development, technology transfer, and manufacturing activities at CDMOs. • Deep understanding of synthetic organic chemistry, process optimization, scale-up principles, and manufacturing support. • Proficient in chemistry-related software and tools, including chemical drawing programs, literature and patent search platforms, Design of Experiments (DoE) applications, analytical software, and project management tools. • Experience with kinetic modelling and process simulation software is considered an advantage. • Familiarity with GMP environments and pharmaceutical development processes is a plus. • Strong organizational, communication, and stakeholder management skills. • Fluent English is mandatory; German language skills are advantageous.
Interested? Then apply today. We look forward to hearing from you!
Please note: Only CVs in English can be accepted and submitted for this role.