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Lead Frontend Engineer @ Zyphra

USOnsiteFull-time
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About this role

Zyphra is an artificial intelligence company based in San Francisco, California.

The Role:As a Lead Frontend Engineer, you’ll lead the design and development of the user-facing side of our agentic system, shaping how users interact with AI across their desktop, browser, and filesystem. You’ll work across interface design, component libraries, and frontend infrastructure to craft seamless, accessible, and intuitive user experiences. You’ll work closely with engineers, ML researchers, and backend teams to bring intelligent agents to life in a way that’s beautifully simple and deeply useful.

You’ll Work Across:Design and development of browser-based and desktop interfaces

Building and maintaining component libraries and styling systems

Researching and refining user flows based on real-world usage and feedback

Prototyping and implementing UI features in collaboration with ML, backend, and systems teams

Making a complex AI product feel simple, accessible, and empowering for a wide range of users

What We're Looking For / Requirements: Strong frontend engineering skills with fluency in HTML, CSS, and JavaScript/TypeScript

Experience with modern frontend frameworks such as React

Demonstrated attention to UI detail and usability, with a user-first mindset

Ability to prototype and iterate quickly, both in code and with design tools like Figma

Experience designing and developing responsive, accessible, and high-performance interfaces

Strong intuition for HCI principles, accessibility, and visual clarity

Excellent collaboration and communication skills—especially with engineers, designers, and ML researchers

Qualifications / Additional Skills:Experience designing or building browser extensions or desktop applications (e.g., Electron, Tauri)

Experience with mobile platforms and responsive design (not required but helpful)

Prior work on products involving complex workflows, automation, or agentic behavior

Interest or experience in backend development, APIs, or AI systems to better interface with the full stack

Familiarity with accessibility standards and inclusive design best practices

A track record of launching polished and user-loved products

Passion for systems-level thinking: building reusable design systems, libraries, and scalable patterns

A clear, opinionated eye for elegant design and user delight

Why Work at Zyphra:Our research methodology is grounded in methodical, step-by-step approaches to ambitious goals. Both deep research and engineering excellence are equally valued

We strongly value new and crazy ideas and are very willing to bet big on new ideas

We move as quickly as we can; we aim to minimize the bar to impact as low as possible

We all enjoy what we do and love discussing AI

Benefits and Perks:Comprehensive medical, dental, vision, and FSA plans

Competitive compensation and 401(k) plan

Relocation and immigration support on a case-by-case basis

In-office snacks and meals provided

Unlimited PTO and company holidays

In-person team in San Francisco with a collaborative, high-energy environment

Skills

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