About this role
Intern, Clinical Pharmacology & Quantitative Science Beschrijving At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals' unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees. Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so. Does this inspire you and feel like a fit? Then we would love to have you join us! The Role Can quantitative modeling help reduce the need for animal studies in drug development? While in vitro assays provide valuable mechanistic insights, they do not always fully predict how a therapy will perform in vivo. Animal studies can bridge that gap, but they are time-consuming, resource-intensive, and should only be used where they truly add scientific value. Within Genmab's Quantitative Translational Pharmacology team, you will contribute to an exciting project that explores how quantitative modeling can help optimize this process. By combining historical preclinical and clinical data, you will investigate whether in vivo tumor growth inhibition studies improve the prediction of efficacious patient exposure compared with an in vitro-only approach. Ultimately, the goal is to support smarter drug development decisions while contributing to the 3Rs principles (Replacement, Reduction and Refinement) by identifying opportunities to reduce or refi...