About this role
Department of Physiology, Anatomy & Genetics (DPAG), Kavli Institute for Nanoscience Discovery, University of Oxford
Location: Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU
Contract: Full-time, fixed-term (7 months)
About the Role
We are seeking a Postdoctoral Research Scientist to join our Laboratory of Molecular Neurodegeneration at the Department of Physiology, Anatomy and Genetics, University of Oxford. The ideal candidate will be a highly motivated and skilled cellular neurophysiologist with experience in the differentiation of human Parkinson’s and control iPSC lines into striatal, dopaminergic and cortical neurons in mono-culture and microfluidic tri-culture, assays of neuronal electrophysiology and calcium signalling, analysis of Parkinson’s cellular phenotypes using high-content imaging in striatal, dopaminergic and cortical neurons, and in molecular cell biology and RNA-Seq single cell gene expression analysis. This post is available for 7 months from December 2026.
Key Responsibilities
Differentiation of human iPSC lines into striatal, dopaminergic and cortical neurons in mono-culture and microfluidic tri-culture Assays of neuronal electrophysiology and calcium signalling Analysis of Parkinson’s cellular phenotypes using high-content imaging in striatal, dopaminergic and cortical neurons Molecular cell biology and RNA-Seq single cell gene expression analysis Contributing to research development and publications
Essential Criteria
PhD or DPhil degree in neuroscience or cell/molecular biology (or near completion) Hands-on expertise in the differentiation of human iPSC lines into striatal, dopaminergic and cortical neurons in mono-culture and microfluidic tri-culture Hands-on expertise in assays of neuronal electrophysiology and calcium signalling Hands-on expertise in analysis of Parkinson’s cellular phenotypes using high-content imaging in striatal, dopaminergic and cortical neurons Hands-on expertise in molecular cell biology and RNA-Seq single cell gene expression analysis Experience of creating collaborative and inclusive environments with people from different backgrounds.
About DPAG
DPAG conducts world-leading research spanning molecular, cellular, tissue, and systems-level physiology, bridging discovery science and translational medicine. The department is committed to research excellence, high-quality teaching, and fostering an inclusive and supportive workplace.
Benefits
The University of Oxford offers a comprehensive benefits package, including:
Hybrid working opportunities Contributory pension scheme 38 days annual leave Childcare and family leave support Cycle and electric vehicle loan schemes Employee Assistance Programme Social and sports club membership Discounted bus travel and season ticket loans
How to Apply
Submit a CV, supporting statement addressing the selection criteria, and details of two referees via the online application system.
Closing date: 12 noon, 24 August 2026
Interviews: Expected via Microsoft Teams during the weeks commencing 31 August 2026.
DPAG welcomes applications from under-represented groups and is committed to equality, diversity, inclusion, and sustainability through initiatives such as LEAF and Green Impact.