About this role
Scientist Bioanalysis Share Department Development ProQR Therapeutics is a NASDAQ-listed biotechnology company headquartered in Leiden, the Netherlands with an office in and Cambridge, Massachusetts, USA. At ProQR, we are on a mission to edit RNA, treat disease and change lives. A team of 180+ enthusiastic ProQRians from all walks of life and more than 30 different nationalities is committed to pioneering transformative RNA therapies to make a difference in the lives of the communities we serve. Our proprietary Axiomer™ RNA editing technology platform enables the editing of specific single nucleotides in RNA using the cells own editing machinery. Axiomer editing technology harnesses ADAR (Adenosine Deaminase Acting on RNA), a protein which is present in all human cells, to repair G-to-A mutations, modulate protein, and enable protective mutation functions. Axiomer could potentially yield a new class of innovative medicines and treat currently untreatable diseases. By harnessing the power of RNA editing, we aim to create a world where genetics inform your health - but never limit it. To strengthen our Axiomer Unit, we are looking for a Scientist Bioanalysis (full-time) to support our translational development portfolio Location: Leiden, NL (on-site) The role: As Scientist Bioanalysis , you will be responsible for developing and executing the bioanalytical strategy for measuring oligonucleotide concentrations and relevant biomarkers in preclinical and clinical samples. Your work will generate critical pharmacokinetic (PK), pharmacodynamic (PD), and biomarker data that support dose selection, target engagement, safety assessments, and the advancement of ProQR's editing therapies into and during clinical development. You will oversee bioanalytical activities performed both internally and externally, ensuring high-quality data are delivered on time and in compliance with applicable regulatory standards. A key aspect of the role ...