About this role
What can we offer you? Apart from job satisfaction, we can offer you:
HEALTH
• Medical, Dental and Vision benefits for you and your family, including Flexible Spending Accounts (FSA)
YOURSELF
• Paid time off policy including holidays and sick time
• Internal growth and development programs & trainings
WEALTH
• 401(k) program, life & accident insurance and disability insurance
We are seeking a motivated and skilled Scientist I to support our invivo imaging studies using small animal models. This role is central to our preclinical research team and involves hands-on work with nuclear medicine (PET/SPECT), computed tomography (CT), and magnetic resonance imaging (MRI). The successful candidate will play a key role in project leadership, with the opportunity to oversee staff and lab spaces. They will also provide technical support across a range of in vivo disease models, perform dosing and surgical procedures, and contribute to team leadership by mentoring junior staff.
This position offers an exciting opportunity to evolve into a strategic leadership role within a fast-paced, collaborative research environment. Whether leading a small team or contributing as a senior individual contributor, you'll have the autonomy to drive research excellence and help shape the future of preclinical imaging studies.
Key Responsibilities
Team Leadership & Staff Development
• Lead or support day-to-day activities within the invivo team, ensuring alignment with project timelines and goals. • May oversee and develop junior staff (2-4 members) provide training and technical guidance as needed. • Contribute to the management and optimization of laboratory space, including equipment and supply maintenance. • Develop, write and enforce laboratory-specific standard operating procedures (SOP’s) • Evaluate study protocols and collaborate with Discovery Research teams during protocol development. • Liaise with IACUC and internal stakeholders to ensure compliance with animal use protocols (AUP’s) • Lead onboarding and integration of new team members.
Study Support & Execution
• Participate in protocol development and review with Discovery Research and cross-functional teams. • Assist in coordinating study scheduling and establish timelines for protocol execution. • Execute a wide range of study types including: • Efficacy, biodistribution, pharmacokinetics, toxicokinetic, and xenograft models.
• Perform dosing and surgical procedures such as: • IV, IP, SC, IM, PO administrations • Perfusion, tissue resection, microdissection • Biological sampling (blood, CSF, organs) • Survival surgery and CNS administration (preferred but not required)
• Assist in image acquisition (PET, SPECT, CT, MRI) and related procedures. • Handle radioactive and BSL2 materials, including sample processing, gamma counting, and proper waste disposal. • Ensure strict adherence to laboratory SOPs and regulatory guidelines (IACUC, radiation safety, lab safety). • Ensure accurate data collection, analysis and reporting. • Maintain complete and clear laboratory records. • Monitor and report on animal health in collaboration with attending veterinarian.
• Represent in vivo operations in meetings and cross-functional communications. Functional Competencies (Technical knowledge/Skills)
• Some understanding of biology, pharmacology, or small animal imaging in the context of pharmaceutical research • Ability to multi-task • Comfort with various computer operating systems and programs • Strong written and oral communication skills • Occasional weekend and after-hours work as needed • Ability to lift 50 pounds Highly Desired Competencies
• Strong proficiency in IV dosing and minor surgical procedures • Microdissection of specific tissues (e.g., lymph nodes, brain sections) • Hands-on experience in a preclinical imaging environment
Experience, Education, and Certifications
• Bachelor’s degree in Biology, Animal Science, or related field, with 7+ years of relevant in vivo research experience or higher degree with 5+ years of relevant in vivo research experience. • Demonstrated experience mentoring laboratory staff. • Competence with computer systems and laboratory data platforms. • Ability to lift up to 50 pounds. • Availability to work occasional weekends as required. • This role is based in the Perceptive office/lab located in Needham, MA. The annual base salary range for this role is $65,305-$121,287. This range represents the anticipated initial annual salary and may vary depending on several factors including the candidate’s experience and skills and may be subject to market rate adjustment.