About this role
Ridgeline Discovery, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international team of >50 highly experienced drug discovery and industry professionals and built and operated multiple new successful companies; these companies have raised significant funds through Series B, IPO and an exit through a trade sale.
We are seeking a highly motivated Bioanalytical Scientist / Research Associate to support the development and execution of bioanalytical strategies for large molecule therapeutics. The successful candidate will play a key role in establishing, developing, qualifying, validating, troubleshooting, and overseeing immunoassays used to support preclinical and clinical studies. This position combines hands-on laboratory work with external study coordination, requiring close collaboration with contract research organizations (CROs), project teams, and cross-functional stakeholders. The ideal candidate is scientifically rigorous, highly organized, and experienced in bioanalytical support for complex biologic modalities.
Key Responsibilities
Bioanalytical Assay Development & Validation
• Design, develop, optimize, qualify, and validate bioanalytical methods for large molecule therapeutics. • Establish, develop, and perform immunoassays, including ligand-binding assays (LBAs) such as ELISA, MSD/ECL, Gyrolab, and related platforms. • Lead assay troubleshooting, root-cause investigations, and implementation of corrective actions. • Generate robust bioanalytical data to support pharmacokinetic (PK), immunogenicity (ADA/NAb), and biomarker assessments. • Ensure assays are fit-for-purpose and compliant with applicable regulatory guidance and industry best practices. • Contribute to the scientific interpretation of bioanalytical data and preparation of study reports. • Analyze, document, and communicate experimental results clearly and accurately. • Maintain relevant laboratory documentation, assay procedures, and validation records.
CRO Management & External Collaboration
• Serve as the bioanalytical point of contact for external CRO partners. • Coordinate assay transfer, method development, qualification, validation, and sample analysis activities conducted by CROs. • Review study protocols, validation plans, data packages, and final reports. • Monitor study timelines, deliverables, data quality, and regulatory compliance. • Collaborate with internal project teams to ensure timely delivery of bioanalytical support across programs. • Provide scientific oversight of outsourced bioanalytical activities and contribute to vendor selection and performance evaluation.
Qualifications
Education
• MSc in Biology, Biochemistry, Biotechnology, Pharmaceutical Sciences, Immunology, or a related field with relevant industry experience; or PhD in a relevant scientific discipline.
Experience
• 3+ years (Research Associate) or 5+ years (Scientist) of relevant experience in bioanalysis of large molecule therapeutics within biotechnology, pharmaceutical, or contract research laboratory environments. • Proven hands-on experience developing, qualifying, validating, overseeing, and troubleshooting immunoassays. • Experience supporting pharmacokinetic, immunogenicity, and biomarker bioanalysis programs. • Experience managing outsourced bioanalytical activities and working effectively with CROs.
Technical Skills
• Strong expertise in ligand-binding assays and immunoassay platforms (ELISA, MSD/ECL, Gyrolab, or equivalent). • Familiarity with regulatory expectations and guidance for bioanalytical method validation. • Strong data analysis, interpretation, and scientific reporting skills. • Experience working in GxP-regulated environments is an advantage. • Experience with MS applications for complex therapeutic modalities is considered a plus
Personal Attributes
• Hands-on, proactive, and solution-oriented scientist. • Strong troubleshooting and problem-solving capabilities. • Excellent organizational and project coordination skills. • Strong communication skills and the ability to collaborate effectively across internal and external teams. • Capable of managing multiple priorities in a dynamic environment.