About this role
Job summary
Clifton Medical Centre, a busy town centre based GP practice in Rotherham, is seeking an enthusiastic GP to join our established primary care research unit on a part-time basis (approximately 5 morning sessions), with flexible working hours considered for the right candidate.
This is an excellent opportunity for a GP looking to step away from the pressures of routine NHS general practice while remaining clinically active and playing a direct role in developing new treatments that improve patient care. You will work alongside an experienced multidisciplinary research team delivering commercial and academic clinical trials across a broad range of therapeutic areas, including obesity, diabetes, cardiovascular disease, respiratory medicine, chronic kidney disease, and other long-term conditions.
Based at our town centre site, the role is primarily clinical, acting as Principal Investigator and/or Sub-Investigator across our trial portfolio, with flexibility to support the wider research team recruitment, data quality, and study delivery during quieter clinical periods. You'll be joining a well-established, supportive practice with strong links to primary care research, offering genuine variety, professional development, and an excellent work-life balance away from routine surgery sessions.
Main duties of the job
The successful applicant will act as Principal Investigator and/or Sub-Investigator on commercial and academic clinical trials. Duties include obtaining informed consent in line with ICH-GCP and study protocols; conducting eligibility assessments including medical history, records review and physical examination; performing protocol-specific examinations at screening and follow-up visits; and reviewing ECGs, laboratory results and other investigations to determine eligibility and ongoing safety.
You will assess adverse events and concomitant medications, determining clinical significance and causality, and will prescribe and manage investigational medicinal products where required. You will provide medical advice and support to the research nursing team and maintain participant safety throughout.
As Investigator, you will maintain medical oversight of delegated studies, ensure appropriate delegation of responsibilities, and participate in sponsor visits, audits and inspections where required.
When clinical commitments allow, you will support the wider team with recruitment, case report form completion, and data quality, working collaboratively within a multidisciplinary team and contributing to training, mentoring and continuous improvement of research processes.
About us
Clifton Medical Centre is a town centre-based GP practice in Rotherham, serving 13,000 patients across two sites. We are a friendly and well-established practice with a strong reputation for high-quality patient care and a supportive, team-based working culture.
Our multidisciplinary team includes GPs, Advanced Clinical Practitioners, Paediatric Advanced Nurse Practitioners, Paramedics, Nurse Practitioners, Practice Nurses, Pharmacists, a Practice Manager, and dedicated Reception and Administrative staff, all working together to deliver comprehensive primary care to our patients.
Alongside our core general practice services, Clifton Medical Centre is home to an established primary care research unit, delivering commercial and academic clinical trials across a range of therapeutic areas including obesity, diabetes, cardiovascular disease, respiratory medicine, and chronic kidney disease. This gives our team the opportunity to combine excellent primary care with involvement in cutting-edge clinical research, contributing directly to the development of new treatments.
We pride ourselves on being a supportive, proactive and forward-thinking practice, and we are committed to the ongoing development of our staff at every level.
Job description Job responsibilities Key Duties and ResponsibilitiesClinical Research Responsibilities
The successful applicant will act as Principal Investigator and/or Sub-Investigator on commercial and academic clinical trials as appropriate. Responsibilities will include:
Obtaining informed consent from study participants in accordance with ICH-GCP and study protocols.
Conducting eligibility assessments, including medical history, review of medical records, physical examination and assessment against study inclusion and exclusion criteria.
Performing protocol-specific medical examinations and assessments at screening and follow-up study visits.
Reviewing ECGs, laboratory investigations and other clinical results to determine participant eligibility and ongoing safety.
Reviewing, signing and interpreting all clinically relevant blood results and investigation reports generated during studies.
Assessing adverse events, serious adverse events and concomitant medications, determining clinical significance, causality, expectedness and any follow-up required.
Prescribing and managing investigational medicinal products where required by study protocols.
Providing medical advice and support to the research nursing team throughout study delivery.
Maintaining participant safety throughout all research activity.
Ensuring studies are conducted in accordance with ICH-GCP, study protocols, sponsor requirements and regulatory standards.
Participating in sponsor initiation visits, monitoring visits, audits and regulatory inspections where required.
Investigator ResponsibilitiesWhere acting as Principal Investigator or Sub-Investigator, the successful applicant will:
Maintain overall medical oversight of delegated studies.
Ensure appropriate delegation of study responsibilities.
Maintain high standards of participant safety and data quality.
Ensure protocol deviations are appropriately documented and managed.
Review and sign relevant study documentation.
Support investigator meetings and mandatory study training.
Supporting the Wider Research TeamThis role is intended to be an integral part of the research team rather than solely a physician role. When clinical commitments permit, the successful applicant will actively support wider study delivery by assisting with tasks such as:
Identifying potentially eligible participants using SystmOne population searches.
Telephoning potential participants to discuss research opportunities.
Supporting participant recruitment and retention initiatives.
Assisting with completion of electronic case report forms and source documentation where appropriate.
Supporting adverse event documentation and follow-up.
Undertaking protocol-defined study visits that do not specifically require a nurse or GP qualification.
Assisting research nurses during busy clinics.
Supporting data quality and query resolution.
Contributing to maintenance of Investigator Site Files and study documentation.
Helping ensure recruitment targets are achieved.
Team ResponsibilitiesThe successful applicant will
Work collaboratively within a highly experienced multidisciplinary research team.
Provide ad hoc clinical advice and guidance to research nurses and clinical trial assistants.
Participate in regular research team meetings.
Contribute to continuous improvement of research processes.
Support training and mentoring of junior members of the research team where appropriate.
Maintain Good Clinical Practice certification and undertake all mandatory study training.
Person Specification
Qualifications Essential
Essential MRCGP or equivalent. Fully registered with the GMC with a licence to practise. Included on the NHS Performers List. Excellent clinical assessment skills. Good Clinical Practice GCP certification or willingness to obtain. Excellent communication and organisational skills. Comfortable working as part of a multidisciplinary team. Good IT skills. Enthusiastic, flexible and willing to undertake a varied role. Desirable Previous experience as a Principal Investigator or Sub-Investigator. Experience of commercial clinical trials. Experience using SystmOne. Experience working within primary care research.
Desirable
Desirable Previous experience as a Principal Investigator or Sub-Investigator. Experience of commercial clinical trials. Experience using SystmOne. Experience working within primary care research.
Disclosure and Barring Service Check This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
UK Registration
Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).
Employer details Employer name Clifton Medical Centre
Address Doncaster Gate
Rotherham
South Yorkshire
S65 1DA
United Kingdom
Employer's website https://www.cliftonmedicalcentre.co.uk/ (Opens in a new tab)