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- Per plaats - Amsterdam Carrière - UMC Utrecht Utrecht €3.724 - €5.867 36 uur WO Gisteren Postdoc position - Unraveling Immune Checkpoint Inhibitor Toxicity and Efficacy UMC Utrecht Salaris €3.724 - €5.867 Uren 36 uur Dienstverband Tijdelijk Werk locatie Utrecht Opleidingsniveau WO Branche Gezondheidszorg/Welzijn Functieomschrijving Join UMC Utrecht as a postdoctoral researcher and investigate why immune checkpoint inhibitors work for some patients but not others. Use the unique UNICIT biobank to advance translational cancer immunotherapy research. Dit ga je doen Immune checkpoint inhibitors (ICIs) have been the largest breakthrough in oncology in the last decade. However, they are effective for only a minority of patients and can cause severe immune-mediated toxicities. Within the UNICIT biobank, we have collected sequential blood, feces, and tissue biopsy samples from more than 600 patients treated with ICIs. This unique resource allows you to investigate the mechanisms behind ICI toxicity and treatment resistance and identify factors that could improve patient outcomes. As a postdoctoral researcher, you will join the research group of Prof. Karijn Suijkerbuijk at the Department of Medical Oncology. The group focuses on clinical and translational research in melanoma and cancer immunotherapy, with a strong emphasis on immune checkpoint inhibitors. You will conduct a research project on ICI toxicity and resistance under the supervision of Prof. Karijn Suijkerbuijk. Alongside your own research, you will contribute to collaborative projects, supervise junior researchers and PhD candidates, and help develop new research proposals to secure future funding. Key responsibilities As a postdoctoral researcher, you will: - Plan, perform, and document experiments. - Analyze and interpret molecular and clinical data. - Present your findings in oral and written presentations. - Collaborate closely with ...

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