About this role
Principal Scientist: Lead and manage a multidisciplinary scientific team of 12-15 FTEs ensuring high-quality project delivery. Handle client communications and independently manage technical calls with global stakeholders. Oversee project planning, execution, timelines, and resource allocation. Provide scientific guidance, troubleshooting, and mentoring to team members. Ensure compliance with quality, safety, and organizational standards. Collaborate cross-functionally to support business and operational goals. Organic Chemist: Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately Peptide Chemist: Hands-on expertise in solid-phase and solution-phase peptide synthesis using automated synthesisers like Syro and Liberty CEM Strong experience in peptide purification, characterisation, and analytical techniques, including HPLC, LCMS, and MS Capable of independently handling medium- to large-scale peptide synthesis (1 g to 1 kg scale) with troubleshooting abilities Skilled in laboratory operations, equipment maintenance, SHE compliance, literature review, and accurate experimental documentation Scaleup Chemist: Experience in process R&D, scale-up synthesis, and purification from gm to kg scale Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities Proficient in 1H NMR, HPLC, and LCMS interpretation Strong project execution and team collaboration skills Antibody Drug Conjugation Chemist (ADC) Synthesis and purification of complex antibody drug conjugate (ADC) molecules Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs Synthesis of highly potent drug molecules – payloads Purification of complex and large molecules by flash column and HPLC Handling various type chemistry with different payloads Interpretation and characterisation of higher molecular weight compounds