smartrecruiters

Immunoassay Development Scientist - Analyte Detection @ Eurofins

Fremont, CA, usOnsiteFull-timePosted 47 days ago

Opens on smartrecruiters

About this role

We are seeking for hands-on immunoassay developers for a new Analyte Detection Business Unit. If you have designed assays from scratch, selected and screened reagent pairs, and solved real development problems across ELISA, MSD, TR-FRET, AlphaLISA, or related formats, we want to hear from you. Here’s what you’ll do:

Laboratory Execution & Technical Support

Design and execute bioconjugation strategies for labeling antibodies and other proteins with donor/acceptor fluorophores (NHS-ester, maleimide, and related chemistries); optimize reaction conditions, purification, and labeling efficiency from first principlesDevelop homogeneous immunoassays (TR-FRET, HTRF, AlphaLISA, MSD, and/or ELISA) for analyte detection; own the full development cycle from reagent selection and antibody pairing through format optimization and matrix validationLead independent antibody screening campaigns to identify optimal capture/detection pairs; apply structured DOE approaches to optimize reagent concentrations, buffer formulations, and assay windowConduct routine assay validation experiments, including precision, accuracy, linearity, and range determinationPrepare biological samples, reagents, and buffers according to SOPsOperate and maintain laboratory equipment, including plate readers, liquid handlers, and analytical instrumentsIndependently diagnose and resolve assay performance failures; apply root-cause analysis to reagent, buffer, and instrument variables and propose data-driven corrective actionsSupport antibody screening and characterization activitiesAssist with benchmarking studies comparing assay performance to competitor productsData Management & Documentation

Maintain detailed, accurate, and organized laboratory notebooks documenting all experimental procedures and observationsAnalyze experimental data using GraphPad Prism, Excel, or similar softwareGenerate clear data summaries, graphs, and tables for internal reports and presentationsContribute to technical reports and validation documentsAssist in drafting sections of SOPs and user manual protocolsEnsure all documentation meets company quality standards and regulatory requirementsCollaboration & Learning

Work collaboratively with Senior Scientist and other team members to support project timelinesParticipate in team meetings and provide updates on experimental progressCommunicate experimental results and technical challenges effectively to the supervisorActively seek learning opportunities to develop technical skills in bioconjugation and immunoassay developmentSupport cross-functional activities with Manufacturing, Quality, and Marketing teams as neededParticipate in training programs to enhance scientific and professional developmentCompliance & Safety

Adhere to all site employee health and safety (EHS) and IT security requirementsDemonstrate and promote the company vision and valuesMaintain regular attendance and punctualityConduct all activities in a safe and efficient mannerPerform other duties as assignedMeet project deadlines and adjust work hours as needed to support team objectives Here is who and what we are are looking for in the ideal candidate:

Education/Experience (BMQ)

BS/MS in chemistry, biochemistry, biology, or related discipline with 3–7 years of hands-on industrial experience developing immunoassays from scratch (ELISA, MSD, TR-FRET/HTRF, AlphaLISA, or equivalent); experience must include reagent selection, antibody screening, and quantitative assay optimization — not solely protocol executionDemonstrated experience independently developing and validating immunoassays — including reagent pair selection, signal-to-noise optimization, and characterization studies — with a verifiable track record of assays taken from concept to validated formatSolid understanding of antibody-antigen binding kinetics, epitope considerations for sandwich vs. competitive immunoassay design, and the impact of protein biochemistry on assay performanceFamiliarity with aseptic technique and cell culture is a plusAbility and/or Skills (BMQ)

Strong laboratory skills with attention to detail and accuracyBasic proficiency in data analysis using Excel; familiarity with GraphPad Prism or similar software is a plusGood organizational and time management skills with the ability to balance multiple tasksAbility to design experiments from first principles, generate and test hypotheses, and translate results into actionable next steps — not limited to following pre-written protocolsStrong work ethic with demonstrated reliability and accountabilityEagerness to learn new techniques and acquire new scientific knowledgeGood verbal and written communication skillsTeam player with positive attitude and willingness to collaborateAbility to work independently on assigned tasks while knowing when to seek guidanceComfortable working in a fast-paced laboratory environment with defined deadlinesAdditional Preferences

Experience developing assays in two or more immunoassay platforms (e.g., ELISA, MSD/ECL, TR-FRET/HTRF, AlphaLISA, Luminex); cross-platform familiarity is a strong differentiatorHands-on bioconjugation experience beyond kit use: NHS-ester, maleimide, aldehyde, or click-chemistry conjugation of small molecules, haptens, or fluorophores to antibodies or proteins, including optimization of degree of labeling (DOL) and purificationHands-on experience with multi-channel pipettes, automated liquid handlers, and plate readersFamiliarity with time-resolved fluorescence or FRET-based detection principles (TR-FRET/HTRF, LANCE, or AlphaLISA); experience with plate reader instrumentation for fluorescence or luminescence readouts (e.g., PHERAstar, EnVision, or equivalent)Academic or industrial research experience in drug discovery, diagnostics, or related areasExperience maintaining detailed laboratory notebooks and documentationApplied experience with Design of Experiments (DOE) for reagent concentration and buffer optimization, not merely theoretical familiarityExperience presenting research findings in laboratory meetings or scientific conferencesDemonstrated problem-solving skills and scientific curiosityProficiency with Microsoft Office Suite (Word, Excel, PowerPoint) Salary Range: $95,000 - $125,000/yr.

Excellent full time benefits including comprehensive medical coverage, dental, and vision optionsLife and disability insurance401(k) with company matchPaid vacation and holidaysEurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.

Skills

Testing & LaboratoryScienceMid-Senior LevelBiotechnology

Ready to apply?

Install the ResuMinder extension and we'll auto-fill the application in seconds — no rewriting.

Get the extension →