About this role
We are seeking a highly skilled, passionate, and motivated scientist to join our Downstream Process Development team. This role will support downstream unit operations and pilot-scale manufacturing campaigns. The ideal candidate will have experience with AAV purification techniques with skills in data analysis and reporting data. The successful candidate will have a desire to succeed at the highest level to develop gene therapies for patients.
Job Responsibilities:
Downstream Process Development & Optimization (greater than 50% effort):
Execute and troubleshoot downstream purification unit operations including affinity chromatography, tangential flow filtration (TFF), ion exchange chromatography, and ultracentrifugation.Perform buffer preparation, sample collection, and in-process testing.Maintain detailed laboratory notebooks and generate technical reports summarizing experimental findings.Pilot-Scale Manufacturing Support (less than 50% effort):
Assist in pilot-scale manufacturing campaigns.Execute batch records with high attention to detail.Perform equipment setup, cleaning, and troubleshooting for pilot-scale unit operations.
Minimum Required Qualifications:
B.S. in life sciences with 4-6 years of industry experience or M.S. in life sciences with 2-3 years of industry experience in downstream bioprocessing.Previous experience in downstream unit operations (chromatography, filtration, centrifugation).Hands-on experience with chromatography techniques including affinity chromatography and IEX.Demonstrate a good understanding of tangential flow filtration (TFF) techniques.Experience with AAV, lentivirus, or other viral vector purification.Knowledge of small and pilot scale process development.Demonstrate critical thinking, be self-motivated, accountable, detail-oriented, have excellent organization and communication skills, and demonstrate the ability to work both independently and as a member of a team.Ability to work effectively with minimal supervision after initial training.Ability to troubleshoot and interpret experimental results and effectively summarize and present conclusions.Ability to work in a laboratory environment and handle occasional light to moderate lifting (up to ~50 lbs).Preferred Qualifications:
Basic knowledge of analytical techniques for protein/viral vector characterization.Knowledge of aseptic techniques and cell culture.Familiarity with Unicorn software.Familiarity with statistical analysis software (JMP, Minitab).Exposure to process automation and single-use technologies.Strong desire to learn new techniques and a willingness to provide upstream cross-training support.
Position is Full Time, Monday-Friday, 8am-5pm. Candidates currently living within a commutable distance of Boston, MA are encouraged to applyWhat to Expect in the Hiring Process:
10-15 Minute Phone Interview with Regional Recruiter45-60 Minute Virtual Interview with Manager and/or Group Leader45-60 Minute In-Person Meeting for a Casual Discussion of the RoleWhat We Offer:
Excellent full-time benefits including comprehensive medical coverage, dental, and vision optionsLife and disability insurance401(k) with company matchPaid vacation and holidaysYearly goal-based bonus & eligibility for merit-based increasesEurofins Lancaster Laboratories Professional Scientific Services® (PSS) is a global, award-winning insourcing solution that places our people at our clients’ sites dedicated to running and managing laboratory services while eliminating headcount, co-employment, and project-management worries.
We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR, and a great place to work best practices, to recruit, hire, train, and manage highly qualified scientists to perform laboratory services using our client’s quality systems and equipment.
To learn more about Eurofins Lancaster Laboratories, please explore our website www.eurofinsus.com.
Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.