About this role
Eurofins PSS is seeking a passionate and dedicated Functional Genomics Scientist with expertise in pooled CRISPR screening and scRNA-seq. The candidate will work directly on the client site in Cambridge, MA and will collaborate with scientists from multiple therapeutic areas (Oncology, Immunology, Neuroscience, Cardiometabolic Disease, Pharmacology, and Chemical Biology) to develop high-throughput cutting-edge genomic technologies to better understand disease mechanisms and to accelerate the discovery of new targets and biomarkers across therapeutic areas. The candidate will utilize innovative genetic screening (CRISPR) and multi-omics single cell sequencing approaches (CROP-seq/Perturb-Seq, REAP-Seq, optical pooled screening) to impact all stages of the pipeline from pre-clinical to clinical development. The candidate will support the client’s dynamic and innovative early discovery research environment and will be expected to work both independently and collaboratively with colleagues.
This is a hands-on position. The ideal candidate shall have excellent lab skills, strong documentation skills, ability to analyze and summarize data to draw conclusions, and make recommendations.
Key responsibilities include but are not limited to:
Design, execute, analyze, and interpret cell-based assays and determine feasibility and best approach for pooled scRNA-seqPerform CROP-seq/Perturb-seq screens with guidance from colleaguesWork closely with bioinformatics groups across MRL to coordinate data transfer and analysisCommunicate progress, results, and conclusions to the group, project teams and other stakeholdersMaintain detailed lab notebook and records of workThis position is lab based and requires 5 days on site and 90% of time in the lab Required:
Ph.D. degree in cell and molecular biology or related scientific discipline with 3+ years of experience in industryExtensive hands-on experience in cell-based assay development and pooled CRISPR screensHands-on experience with scRNA-seq sample generationWorking knowledge and experience in molecular biology assays, especially next generation sequencing and/or other high throughput genomic technologiesAttention to detail and strong ability to troubleshoot and optimize novel methodsExcellent communication (oral and written) skills including an ability to effectively communicate experimental design, results, and conclusionsAbility to work independently, but also an ability to work effectively in a collaborative and multidisciplinary environmentSelf-motivated and capable of prioritizing deliverables among multiple simultaneous projectsDrug discovery experience in biotech and/or pharmaceutical industry, experience working in a highly matrixed organizationPreferred:
Experience analyzing single cell sequencing data sets (CROP-seq/Perturb-seq)Experience with optical pooled screening, high content phenotypic screens and image analysis What to Expect in the Hiring Process:
10-15 Minute Phone Interview with Region Recruiter45-60 Minute Virtual Interview with Manager and/or Group Leader45-60 Minute Onsite to Meet the Team The position is Full Time, Monday-Friday, 8am-5pm. Candidates currently living within a commutable distance of Cambridge, MA, are encouraged to apply.
What We Offer:
Excellent full-time benefits, including comprehensive medical coverage, dental, and vision optionsLife and disability insurance401(k) with company matchPaid vacation and holidaysYearly goal-based bonus & eligibility for merit-based increasesCompensation is $130,000-137,000 annually Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.