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Director, Clinical Program Lead @ Mediartherapeutics

Boston, MassachusettsOnsiteFull-time
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About this role

Reporting to the Head of Clinical Operations, the Clinical Program Lead plays a pivotal role in shaping and driving clinical development programs from inception through regulatory submission. This role requires a versatile, resourceful professional with a proven ability to manage multiple responsibilities, adapt to changing priorities, and execute effectively in a lean organization. The Clinical Program Lead partners closely with internal and external stakeholders to ensure successful trial execution and program advancement.

Responsibilities

• Develops and executes the clinical operations strategy for assigned programs, ensuring alignment with corporate objectives and regulatory requirements.

• Leads cross-functional teams, fostering collaboration with internal and external stakeholders to deliver high-quality clinical trials on time and within budget.

• Oversees program operations, including protocol development, CRO and vendor management, study timelines, budgets, and quality metrics.

• Provides expert input on clinical documents, regulatory submissions, and key regulatory meetings (e.g., INDs, NDAs, BLAs, End-of-Phase 2 meetings).

• Monitors emerging clinical data, assesses risks, and adapts strategies to optimize outcomes.

• Builds and maintains relationships with key opinion leaders, investigators, and collaborators.

• Leads program-level oversight of strategic partners and vendors to ensure compliance with GCP/ICH guidelines and corporate standards.

• Manages and mentors Clinical Operations team members, providing training and leadership development.

• Identifies and drives process improvements to enhance clinical development efficiency and effectiveness.

• Communicates program status, risks, and mitigation plans to senior leadership, enabling informed decision-making.

Qualifications

• Bachelor’s degree or equivalent clinical experience required

• 7+ years of experience in clinical development, including leadership roles in biotech, pharma, or CRO settings, with at least 2 years in a startup environment

• Proven experience in early-phase clinical studies and/or late-phase global or international programs. Experience across multiple therapeutic areas is a plus.

• Strong expertise in clinical trial design, clinical operations, and regulatory requirements.

• Demonstrates adaptability, problem-solving skills, and a hands-on approach in a lean, fast-paced environment.

• Excellent leadership, organizational, and strategic thinking skills.

• Strong interpersonal and communication skills, with the ability to work cross-functionally and influence key stakeholders.

• Line management experience and mentoring abilities are advantageous.

$200,000 - $215,000 based on experience and level that you're hired at.

Skills

R&D

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