About this role
Full time: 35 hours per week Fixed term: 12 months The opportunity: The laboratory of Prof Steven Pollard explores molecular and cellular mechanisms that regulate neural stem cells and how these become deregulated in brain cancers. We now a postdoctoral research position available to explore the transcriptional and epigenetic mechanisms underpinning glioblastoma, with a focus on the SOX family of transcription factors and the role of histone regulation in driving disease. We will explore novel strategies to target the chromatin landscapes using innovative gene therapy approaches. You will build on our recent discoveries that have identified key transcription factors, regulatory enhancers and epigenetic reconfigurations underpinning glioblastoma. Specifically, you will use a combination of the latest biochemical, genome editing and genomics technologies, to dissect the mechanisms underlying the identity of glioblastoma stem cells and roles of key histone regulatory pathways. This kno...